AGM CAS lock / launch troubles

So I know how the AGMs work, have had them for ages now on both F16C and J39C.

Issue that I am struggling with and for the life of me can not figure out is that in Realistic test flight the AGMs work perfect, can even 3rd person lock and launch them on target. When I get in game it just says “nah, not gonna”.

Only thing I can maybe think of is latency affecting the lock / launch? Anyone else maybe have a thought or idea of what I can look at? I usually sit on 140ms to EU and about 220 to NA.